Cationic O-ethylphosphatidylcholines and their lipoplexes: phase behavior aspects, structural organization and morphology
نویسندگان
چکیده
منابع مشابه
Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity.
Mechanisms of cationic lipid-based nucleic acid delivery are receiving increasing attention, but despite this the factors that determine high or low activity of lipoplexes are poorly understood. This study is focused on the fine structure of cationic lipid-DNA complexes (lipoplexes) and its relevance to transfection efficiency. Monocationic (N-(1-(2,3-dioleoyloxy)propyl),N,N,N-trimethylammonium...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2003
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(03)00135-4